Home / Jobs / Biochemical Engineering Jobs - BioChem Adda / BioChemistry PostDoctoral Researcher Job Available @ Sutro Biopharma USA
BioChemistry PostDoctoral Researcher Job Available @ Sutro Biopharma USA

BioChemistry PostDoctoral Researcher Job Available @ Sutro Biopharma USA

BioChemistry PostDoctoral Researcher Job Available @ Sutro Biopharma  USA: Sutro Biopharma, Inc. develops best-in-class antibody drug conjugate and multi-specific antibody-based therapeutics for cancer therapy. Sutro’s discovery and development efforts are driven by the Xpress CF™ platform, a biochemical synthesis system that enables rapid and systematic evaluation of protein structure-activity relationships. Sutro’s make-test cycle for hundreds of protein variants, including those incorporating non-natural amino acids, takes approximately two weeks, enabling broader and deeper biologics discovery and development efforts than can be accomplished with current cell-based expression technologies. Once identified, production of protein drug candidates can be rapidly and predictably scaled in Sutro’s cGMP manufacturing facility. In addition to developing its own drug pipeline, Sutro Biopharma is collaborating with select pharmaceutical and biotech companies to discover and develop novel therapeutics. BioChemistry PostDoctoral Researcher Job Available @ Sutro Biopharma  USA

BioChemistry PostDoctoral Researcher Job Available @ Sutro Biopharma  USA

Date of Posting: 24/03/2017

Post-Doctoral Researcher, Platform Technology Development

  • The Post-Doctoral Researcher will be focused on deepening our fundamental understanding of the biochemical processes underpinning protein production in our XpressCF™ system. In particular, we are interested in increasing the productivity and efficiency of the platform through better understanding and control of transcription, translation and metabolism in the cell free reaction.
  • Characterize key biochemistry elements of the XpressCF™ system and biological reagents (e.g. ribosomes, tRNA)
  • Characterize the transcription and translation systems over the course of the XpressCF™ reaction and use this knowledge to identify potential improvements to the system or process.
  • Conduct experiments to identify bottlenecks and limitations in cell-free metabolism. Leverage this knowledge to predict changes to the strain background or reaction mixture.
  • Identify and characterize key elements (e.g. reagent composition) in fermentations and in vitro transcription and translation reactions. Leverage knowledge to improve biochemical reactions for core technologies at Sutro Biopharma. Work with Protein Biochemistry and Process Development.
  • Present written and oral reports regularly. Based on experimental outcomes, prepare manuscripts for publication in journals or patent applications.

BioChemistry PostDoctoral Researcher Job Available @ Sutro Biopharma  USA

Background/Skillset of ideal candidate

  • Ph.D. in Chemistry or Biochemistry, Molecular Biology, Bioengineering or a related discipline
  • A strong analytical background including HPLC and MS with knowledge of proteomics or metabolomics preferred
  • Experience working with proteins including experience with common protein analytical and biochemical methods
  • Experience working with Ribosomes, RNA and/or DNA is preferred
  • Proficiency with statistical analysis techniques including design of experiments is required.
  • Strong understanding of bacterial biochemistry and metabolism
  • Experience working in multi-disciplinary teams and taking lead of project are pluses
  • Good organizational and problem solving skills
  • Good written and oral communication skills are essential.

Interested Candidates

Please send your jobs@sutrobio.com and reference requisition #1713 in your email. SF Bay Area, no relocation. Sutro offers a competitive compensation package, including health benefits. Application deadline is April 15, 2017.

BioChemistry PostDoctoral Researcher Job Available @ Sutro Biopharma  USA

View Original Notification: http://www.sutrobio.com/post-doctoral-researcher-platform-technology-development/

Check Also

Developmental and Evolutionary Biology & Genetics Postdoc Job Available @ Max Planck Germany

Developmental and Evolutionary Biology & Genetics Postdoc Job Available @ Max Planck Germany

Developmental and Evolutionary Biology & Genetics Postdoc Job Available @ Max Planck Germany: The Max …

BioChem Adda is made possible by displaying online advertisements to our visitors.
Please consider supporting us by disabling your ad-blocker.
%d bloggers like this: