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Cell Signalling Medical Science PhD Fellowship Available @ Copenhagen University Denmark

Cell Signalling Medical Science PhD Fellowship Available @ Copenhagen University Denmark

Cell Signalling Medical Science PhD Fellowship Available @ Copenhagen University Denmark: With over 40,000 students and more than 9,000 employees, the University of Copenhagen is one of the largest institutions of research and education in the Nordic countries.

Cell Signalling Medical Science PhD Fellowship Available @ Copenhagen University Denmark

PhD fellowship in Cell Signaling

About CPR and the research Group

Novo Nordisk Foundation Center for Protein Research (CPR) at the Faculty of Health and Medical Sciences, University of Copenhagen, has been established to promote basic and applied discovery research on human proteins of medical relevance. The Center comprises a wide range of expertise and skills, from proteomics, bioinformatics, high-content microscopy, and high-throughput protein production for functional dissection of complex signaling systems.

Cell Signalling Medical Science PhD Fellowship Available @ Copenhagen University Denmark

The “Proteomics and Cell Signaling” group at CPR is led by Group Leader Prof. Chunaram Choudhary. The Choudhary group works closely with other groups at CPR, especially with the “Clinical Proteomics” group led by Prof. Matthias Mann. The Choudhary group applies cutting-edge mass spectrometry (MS)-based technologies for unbiased identification and quantification of posttranslational modifications, such as ubiquitylation, phosphorylation and acetylation. Using these approaches, we study cell signaling at a “systems-level” in response to different perturbations (such as growth factor stimulation, chemical and genetic perturbations etc.). We use CRISPR-based genome editing for mapping protein-protein interactions and for functional investigations of lead hits from proteome-wide screens. In addition to the state-of-the-art mass spectrometry, the laboratory is equipped with the cutting-edge infrastructure for molecular biology, cell biology and biochemistry work. The Center offers the latest technologies and expertise for genome-wide screens, the next-generation nucleic acid sequencing, high-resolution microscopy, live cell imaging, and protein biophysical characterizations. Our group is technically and internationally diverse and embedded in excellent environment for high-quality research and collaboration. The group consistently publishes in top-ranked journals and has outstanding track-record in in training the next generation of researchers. We are now looking for a highly motivated PhD fellow to join our research group.

Please find more information about the group here:
www.choudharylab.org
http://www.cpr.ku.dk/research/proteomics/choudhary/

Project Description

The candidate will use a combination of the cutting-edge proteomics and CRSPR-based genome editing methods to investigate the dynamics and functions of ubiquitylation and acetylation in genetically defined cell models. Among other tasks, this will include generation of knockout cell lines, affinity-tagging of endogenous proteins, mass spectrometry-based analysis of protein-protein interactions and proteome-wide quantification of PTMs. The candidate is expected to apply various biochemical and molecular biology approaches for biological follow-up experiments on novel and interesting findings derived from large-scale proteomic screens.

Tentative start date: October 1, 2017 or later.

Qualifications

  • The candidate is required to have a M.Sc. or equivalent degree in natural or medical science.
  • Excellent academic track record.
  • Prior experience in molecular biology, biochemistry, and cell culture techniques is required.
  • Knowledge in one or more of the following area(s) would be considered an advantage: cell signaling, chromatin biology, bioinformatic analysis of biological dataset, or experience in mass spectrometry-based proteomics.
  • Good communication skills, both oral and written.
  • An analytical aptitude for devising innovative scientific and technical solutions.
  • To be considered for the position as PhD fellow, it is a condition, that your Master of Science degree is considered to be equivalent to a Danish Master of Science (http://fivu.dk/en).

Place of employment and work

The employment is at CPR (www.cpr.ku.dk), University of Copenhagen, located in central Copenhagen. The research environment at CPR is ambitious and international, with approx. 30 different nationalities currently represented. The Center comprises modern laboratories, supercomputer resources and state-of-the-art facilities within protein science, including microscopy, cryoelectron microscopy, and the next generation sequencing. Seminars with high-profile international speakers and regular internal research seminars are organized at the Center. For more information on working and living in Denmark visit www.ism.ku.dk (International staff mobility) and www.workingconditions.ku.dk

Employment terms and salary

Duration: The duration of the positions is 3 years. It is conditioned upon the candidates’ success­ful enrolment in the PhD programme. This requires submission and acceptance of an application for the specific project formulated by the candidate. The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the University’s rules on achieving the degree. Salary, pension and terms of employment are in accordance with the agree­ment between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary begins around 26,000 DKK (ca. 3.450 EUR) plus 17% pension.

Application procedure

Your application must be submitted electronically by clicking ‘Apply now’ below or via http://employment.ku.dk/faculty/

Your application should include the following documents:

  • Cover letter
  • Curriculum vitae, incl. educational qualifications, experience, publications (if any), language skills and other skills relevant for the position
  • A certified/signed copy of Master of Science certificate. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor will do
  • Names and contact details for two referees
  • The applicants can submit these materials in the given fields in the online submission system, or the application documents can be combined and submitted as a single PDF file. We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the above-mentioned requirements and that do not have a least one publication as first author.

Deadline for application: September 10, 2017

After the expiry of the application deadline, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

Assessment: The selected applications will be assessed according to the Ministry Order on the Appointment of Academic Staff at Universities 2012 and the University of Copenhagen’s guidelines 2013. The Assessment Committee makes a non-prioritized assessment of the academic qualifications and experience with respect to the above mentioned area of research, techniques, skills and other requirements listed in the advertisement.

You can read about the recruitment process at www.employment.ku.dk

For further information about the process, or if you experience any technical difficulty with the online submission system, please contact SUND HR:

sund-hr-cpr@sund.ku.dk

CPR and the University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.

Cell Signalling Medical Science PhD Fellowship Available @ Copenhagen University Denmark

Apply Now: https://candidate.hr-manager.net/ApplicationInit.aspx?cid=1307&ProjectId=145694&DepartmentId=18997&MediaId=4636&SkipAdvertisement=true

View Original Notification: http://employment.ku.dk/phd/?show=145694

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