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ERC Funded PostDoc Job | Computational Biology | @ KU Leuven Belgium

ERC Funded PostDoc Job | Computational Biology | @ KU Leuven Belgium

ERC Funded PostDoc Job | Computational Biology | @ KU Leuven Belgium: The University of Leuven was founded at the centre of the historic town of Leuven in 1425, making it Belgium’s first university. After being closed in 1797 during the Napoleonic period, the Catholic University of Leuven was “re-founded” in 1834, and is frequently, but controversially, identified as a continuation of the older institution.A In 1968 the Catholic University of Leuven split into the Dutch-language Katholieke Universiteit Leuven and the French-language Université catholique de Louvain, which moved to Louvain-la-Neuve in Wallonia.

ERC Funded PostDoc Job | Computational Biology | @ KU Leuven Belgium

ERC FUNDED POSTDOC: ENHANCER CONTROL
(Ref. BAP-2017-107)

Occupation: Full-time
Period: Fixed-term contract
Place: Leuven
Apply no later than: March 31, 2017
For the Laboratory of Computational Biology we are looking for a

ERC FUNDED POSTDOC: ENHANCER CONTROL

The Laboratory of Computational Biology (Stein Aerts lab) at the VIB Center for Brain and Disease Research, and the KU Leuven Center for Human Genetics, is seeking a highly motivated Postdoc to study enhancer logic and to decipher genomic regulatory programs underlying dynamic processes.
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Responsibilities

You will use a combination of high-throughput techniques, including RNA-seq, ChIP-seq ATAC-seq, and massively parallel enhancer-reporter assays (MPRA) to identify and characterize enhancers in animal genomes. These data will be used to train new “enhancer models” using machine learning approaches, to block enhancers using CRISPR-Cas9 techniques, and to synthesize enhancers with new functions. As model system, you will use dynamic state transitions of human cancer cells, in vitro and in vivo.

Profile

  • PhD in LifeSciences, Bio-Engineering, Biomedical Science, or similar.
  • Strong experience or interest in gene regulation.
  • Strong molecular biology and genetics skills, including cloning (Gateway/Infusion, BAC) and CRISPR-Cas9.
  • Experience with cell culture, mouse or Drosophila genetics is a plus.
  • Experience with next-generation sequencing, transcriptomics, epigenomics and bioinformatics is also considered as a plus.
  • Fluency in written and spoken English is required.

Offer

  • A stimulating international research environment.
  • A renewable contract.
  • Competitive salary and benefits.
  • Relocation support possible for international applicants.
    Interested?

For more information please contact Prof. dr. Stein Aerts, tel.: +32 16 33 07 10, mail: stein.aerts@kuleuven.vib.be.

To Apply: 

You can apply for this job no later than March 31, 2017 via the online application tool

View Original Notification: https://icts.kuleuven.be/apps/jobsite/vacatures/54092404

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