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Evolutionary Biology Postdoc Job @ Max Planck Institute Germany

Evolutionary Biology Postdoc Job @ Max Planck Institute Germany

Evolutionary Biology Postdoc Job @ Max Planck Institute Germany: The Max Planck Institute for Evolutionary Biology consists of the three departments Evolutionary Ecology, Evolutionary Genetics and Evolutionary Theory (to be set up). It is focused on basic research to unravel general evolutionary processes, such as ecological adaptations, benefits of sexual reproduction or evolution of cooperation. The scope of the work includes ecological, organismic, molecular and theoretical approaches.

Evolutionary Biology Postdoc Job @ Max Planck Institute Germany

Max Planck Institute for Evolutionary Biology, Plön

Developmental and Evolutionary Biology & Genetics
Microbiology & Ecology
Plant Research
(13/2016)

Type of Job: Scientist

Post-doc (m/f) – theoretical evolutionary biology and evolutionary genomics

Job offer from September 20, 2016

The Max Planck Institute for Evolutionary Biology in Plön (Schleswig-Holstein), Germany, is an internationally oriented research institute and is looking for a
post-doc (m/f) in theoretical evolutionary biology and evolutionary genomics.

A post-doctoral position is available for two years in the field of theoretical biology and evolutionary genomics with the Max Planck research group “Environmental Genomics” headed by Prof. Eva H. Stukenbrock. The Max Planck group is affiliated with the Max Planck Institute for Evolutionary Biology in Plön and the Christian-Albrechts University of Kiel in the North of Germany. The position is funded by the German Research Foundation, DFG, in the framework of the Priority Program “Rapid Evolutionary Adaptation – Potentials and Constraints”. The project will be conducted in close collaboration with Prof. Wolfgang Stephan, Museum für Naturkunde, Berlin, Germany.

Background

Antagonistic co-evolution between pathogens and their hosts can drive rapid adaptive changes in both partners. In this project we aim to understand the underlying mechanisms that drive rapid adaptation in two closely related fungal plant pathogenic species Zymoseptoria tritici (pathogen of cultivated wheat) and Z. ardabiliae (pathogen of wild grasses). These two species differ not only in terms of host and environment (agro-ecosystem versus natural grassland) but also in terms of demography. Our previous analyses have documented a high effective population size in Z. tritici and a strong impact of natural selection on genome evolution.

In this project we aim to investigate the role of recombination in rapid adaptation of Z. tritici and Z. ardabiliae. Comparing patterns of genome evolution in the two species that exist in contrasting environments will allow us to address the impact of ecological constraints on evolution of pathogens. We have used a population genomic approach to infer the genomic recombination landscape in the two species and show the presence of dynamic recombination hot spots in coding sequences in both species. In this project we aim to identify signatures of positive selection in the genomes of Z. tritici and Z. ardabiliae using composite likelihood ratio (CLR) statistics and modeling. A particular goal is to infer the genome-wide distribution of selective sweeps accounting for demography in the two species and we will correlate this information with recombination maps to assess the importance of recombination to adaptive evolution. The development and application of appropriate models will be conducted with Prof. Wolfgang Stephan.

Relevant Literature

  • Wilches R, Voigt S, Duchen P, Laurent S, Stephan W (2014) Fine-mapping and selective sweep analysis of QTL for cold tolerance in Drosophila melanogaster. G3: Genes| Genomes| Genetics 4(9):1635-1645
  • Stukenbrock EH, Bataillon T, Duthei JY, Hansen TT, Li R, Zala M, McDonald BA, Wang J, Schierup MH (2011). The making of a new pathogen: Insights from comparative population genomics of the domesticated wheat pathogen Mycosphaerella graminicola and its wild sister species. Genome Research 21.12 (2011): 2157-2166
  • Stukenbrock EH, Banke S, Javan-Nikkhah M, McDonald BA. 2007. Origin and domestication of the fungal wheat pathogen Mycosphaerella graminicola via sympatric speciation. Molecular Biology and Evolution 24: 398-411
  • Kim Y, Stephan W (2002).
 Detecting a local signature of genetic hitchhiking along a recombining chromosome. Genetics 160: 765-777

Description

  • The candidate should have a PhD in the field of population genetics with expertise in population genomics analyses and theoretical modeling.
  • Proficiency in Linux scripting, in a major programming language and in handling large datasets are needed.
  • The selected candidate will have the opportunity to collaborate with a team of biologists (molecular biologists, evolutionary biologists and population geneticists) as well as to pursue unique research in the fields of population genomics and evolutionary genomics of pathogenic fungi as well as theoretical population genetics.

For further information please contact Eva Stukenbrock (stukenbrock@evolbio.mpg.de).

Your application

The Max Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals.

The Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply.

This position requires a highly self-motivated candidate with excellent oral communication skills and great interpersonal skills.

To Apply:

Interested candidates should send a motivation letter including a description of current research directions, an up-to-date CV, together with the names and the contact information of two references to Eva H. Stukenbrock as a pdf-file.

Application deadline is October 15th, 2016, however the position will remain open until filled by a qualified candidate.

Max-Planck-Institut für Evolutionsbiologie
Prof. Dr. Eva Stukenbrock
August-Thienemann-Str. 2
24306 Plön
Deutschland

 

Evolutionary Biology Postdoc Job @ Max Planck Institute Germany

View Original Notification: http://www.evolbio.mpg.de/3138369/job_full_offer_10741123?c=2169

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