Grade: G

The Department of Pediatrics, Division of Neonatology at Stanford University is seeking a Life Science Research Professional 2 to join Dr. Anca Pasca’s laboratory to perform more complex functions and activities involved in defined research projects, and independently conduct a portion of the research project(s).

The research focus of the lab is to understand molecular mechanisms underlying neurodevelopmental disorders associated with premature birth and neonatal brain injury with the long-term goal of translating the lab’s findings into therapeutics. The research team employs a multidisciplinary approach involving genetics, molecular and developmental neurobiology, animal models and neural cells differentiated from patient-derived induced pluripotent stem (iPS) cells. In particular, the lab is using a powerful 3D human brain-region specific organoid system developed at Stanford (Nature Methods, 2015; Nature Protocols, 2018) to ask questions about brain injury during development.

The candidate for this position should have experience with human stem cells, genome engineering in human cells (CRISPR/Cas9) and/or neural differentiation, and will contribute to exciting projects in the lab aimed at understanding how specific environmental insults or genetic variants contribute to neonatal brain injury.

Duties include: 

• Independently conduct a portion of the research project(s). Make recommendations on experimental design and/or research direction to principal investigator. 
• Independently conduct complex (lab and/or field) experiments to gather data for a portion of a major research project. 
• Interpret and analyze results, often where few guidelines exist, and make modifications to existing procedures and protocols. 
• Develop new research protocols where appropriate protocols are not described in the literature or where modification or adaptation of standard procedures and protocols is required. 
• Perform ongoing literature review to remain current with new procedures and related research; apply to ongoing research and development of new protocols. 
• Contribute substantively to the preparation of papers for publication, especially in the results section, and to publication of findings. Present ongoing work to colleagues and/or academic conferences. 
• Work with health and safety department to ensure lab complies with regulations and all required trainings. 
• Supervise (either formally or informally) staff or students as needed, including oversight and direction on techniques, as well as consultation on project work. Serve as a technical resource for other research staff.
• Oversee the daily activities of the laboratory including lab maintenance; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed. May assist with purchasing laboratory equipment.

*- Other duties may also be assigned

DESIRED QUALIFICATIONS: 
• Master degree or doctoral degree in Biological Sciences.
• Knowledge and experience with stem cell biology, molecular and cell biology techniques including CRISPR/Cas9 genome editing and neural differentiation. 

EDUCATION & EXPERIENCE (REQUIRED): Bachelor’s degree in related scientific field and two years of relevant work experience; or Master’s degree in a related scientific field.

KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):

• Comprehensive understanding of scientific principles. 
• General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
• Strong analytical skills and excellent judgment.
• Ability to maintain detailed records of experiments and outcomes.
• Ability to work under deadlines with general guidance is essential. 
• Excellent organizational skills and demonstrated ability to accurately complete detailed work.

CERTIFICATIONS & LICENSES: Add here

PHYSICAL REQUIREMENTS*:
• Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds. 
• Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts. 
• Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls. 
• Must have correctible vision to perform duties of the job.
• Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
• Ability to lift heavy objects weighing up to 50 pounds.
• Ability to work in a dusty, dirty, and odorous environment.
• Position may require repetitive motion.

*- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

WORKING CONDITIONS:

• May require working in close proximity to blood borne pathogens.
• May require work in an environment where animals are used for teaching and research.
• Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present. 
• Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator. 
• May require extended or unusual work hours based on research requirements and business needs

Life Science Rsch Prof 2 @ Stanford University USA

To Apply & View Original Notification:
https://careersearch.stanford.edu/jobs/life-science-rsch-prof-2-6059

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