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Life Sciences Jobs | Associate Research Scientist @ inStem: Master's degree in discipline of life sciences with 1-3 years of work experience. Cloning.......

Life Sciences Jobs | Associate Research Scientist @ inStem

Life Sciences Jobs | Associate Research Scientist @ inStem: The Institute for Stem Cell Biology and Regenerative Medicine (inStem), is a state-of-the-art research institute in Bangalore, India, dedicated to the study of stem cell and regenerative biology. An autonomous institute funded by the Dept of Biotechnology, Govt. of India, inStem emphasizes collaborative research in stem cell biology. inStem’s mandate to allow this cross-disciplinary, multi-pronged approach to research, straddles the divide between clinical and laboratory research in stem cell biology. In trying to answer intractable and challenging questions that face the field, inStem seeks to rewrite the paradigm of the research institute: without barriers and across disciplines.

Associate Research Scientist

KNOWLEDGE, EXPERIENCE AND SKILLS:

  • Master’s degree in discipline of life sciences with 1-3 years of work experience
  • Substantial experience in protein chemistry through cloning, recombinant protein expression, purification and crystallization is essential

JOB DESCRIPTION:

  • In this position you will specialize in cloning, expression, purification and characterization of challenging recombinant proteins. Position requires coordinated effort with screening and structural biology to elucidate molecular nature of the protein-ligand and protein-drug interaction.
  • Hands on experience in cloning, recombinant protein expression and purification
  • Coordinate cross-departmental activities for the effective use of purified proteins
  • Provide support in biophysical characterization of protein-ligand and protein-small molecule interaction
  • Support and enable reproducible large-scale protein purifications in quantity and quality suitable for X-ray crystallography
  • Regular data analysis, project updates, literature survey and presentations on the target
  • Participate in project team meeting and contribute to the projects intellectually
  • Experience in crystallization and solving protein structure by X-ray diffraction and related tools would be an advantage
  • Working knowledge of instruments such as protein fermenter, FPLC, circular dichroism, isothermal calorimetry, dynamic light scattering, Surface Plasmon resonance etc
  • Maintenance of good laboratory practices in work environment

Life Sciences Jobs | Associate Research Scientist @ inStem

ESSENTIAL DUTIES AND JOB FUNCTIONS:

  • Working knowledge of affinity purification, gel filtration, FPLC, AKTA, SPR and isothermal calorimetry
  • Support protein design, expression and purification to support small-molecule discovery
  • Provide support towards biophysical characterization of proteins and protein-ligand complexes to facilitate protein crystallization and protein science studies
  • Ensure regular supply of quality proteins for screening as well as structural biology efforts
  • Computer skills with extensive experience in data management, data analysis and statistical analysis
  • Must be detail oriented, well organized, and have strong communication skills
  • Excellent teamwork skills and the ability to work in a fast-paced, multi-disciplinary environment

HOW TO APPLY: Interested candidates may send in the following information by email to jobs-ccbt@instem.res.in

  • Curriculum Vitae (CV)
  • Publication list
  • Contact details of three professional referees

Date of Posting: 22-06-2016

Life Sciences Jobs | Associate Research Scientist @ inStem

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