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Medical Microbiology Doctoral Scholarship Position @ Antwerp University Belgium

Medical Microbiology Doctoral Scholarship Position @ Antwerp University Belgium

Medical Microbiology Doctoral Scholarship Position @ Antwerp University Belgium: The University of Antwerp is a young, dynamic and forward-thinking university. It integrates the assets of its historic roots with its ambition to contribute positively to society. The University of Antwerp develops, provides access to and disseminates scientific knowledge through research, teaching and service to society. It carries out these tasks in a spirit of academic freedom and responsibility. Medical Microbiology Doctoral Scholarship Position @ Antwerp University Belgium

Medical Microbiology Doctoral Scholarship Position @ Antwerp University Belgium

2017BAPFGGWEF182 – doctoral scholarship holder in the area of Medical Microbiology

The Faculty of Medicine and Health Science/Vaccine & Infectious Disease Institute at the University of Antwerp is seeking to fill a full-time (100%) vacancy in the Laboratory of Medical Microbiology for a doctoral scholarship holder in the area of Medical Microbiology.

Medical Microbiology Doctoral Scholarship Position @ Antwerp University Belgium

Investigating medically relevant biofilms using state-of-the-art molecular techniques

A PhD position is vacant at the Laboratory of Medical Microbiology (LMM), Vaccine & infectious Disease Institute, University of Antwerp under the supervision of Prof. Dr. Surbhi Malhotra-Kumar and Prof. Dr. Herman Goossens. One of the main research tracks of LMM focuses on investigating the role of biofilms in healthcare settings.

Biofilm formation on indwelling medical devices and implants pose a critical medical problem. Bacteria in biofilm behave differently from planktonic bacteria, especially in terms of their response to antibiotic treatment. Bacteria in biofilm could also adopt a slow growing or starved state due to the altered microenvironment such as depletion of nutrition and accumulation of waste. This difference in physiological behavior generates serious consequences for therapy of biofilm-associated infections. In addition to the difficulty of treating biofilms with conventional antibiotic therapy, treatment is further hindered by the rising antibiotic resistance among pathogens.

Project

The project will focus on methicillin resistant Staphylococcus aureus (MRSA), a multi-drug resistant pathogen that is associated with infections with a strong biofilm component. This project aims to achieve a thorough understanding of the mechanisms involved in the process of antibiotic resistance, including the effects of the overall microbial community on gene expression. More specifically, how such interactions lead to increased biofilm formation or the expression of virulence factors as such influencing the response to treatment. These data could lead to the development of anti-biofilm therapies that are superior to the current antibiotic treatment. In addition, novel candidate genes with potential as anti-biofilm and/or antipersistence targets will be identified with the aim of developing the basis for new therapeutic and/or diagnostic interventions. These studies will utilize both next-generation technologies as well as in-house available transposon libraries, phage transduction and other gene manipulation techniques to investigate MRSA biofilms in great detail.

Profile and requirements

  • You hold a master degree in Bio-engineering, Biomedical sciences, Pharmaceutical sciences, Biochemistry, Biology, Biotechnology or equivalent degrees.
  • You have graduated with at least one distinction grade
  • You have a strong interest in bacteriology and/or infectious diseases
  • You can work both independently as well as in an international team
  • You have the ability to accurately plan and perform laboratory experiments
  • You have strong analytical thinking skills, an appropriate problem solving attitude, can approach complex issues in a systematic way and is a good planner to meet milestone and deliverable deadlines
  • You are willing to travel abroad for short training periods or to international scientific meetings to present research results.
  • Fluency in English is required

We offer

  • a doctoral scholarship (Dehousse mandate) for a period of 4 years
    place of work is Campus Drie Eiken, Universiteit Antwerpen, Antwerp, Belgium
    funding for the project has been granted with a gross monthly grant ranging from € 2.280,27 – € 2.419,84; however, the PhD student will be encouraged to apply for a national (IWT and/or FWO) doctoral scholarship
  • a dynamic and stimulating work environment.

How to apply?

Please send your application, accompanied by your CV and cover letter, to Debbie.Wils@uantwerpen.be, until the closing date 31st August 2017.

For questions about the profile and the description of duties, please contact Inge Dierynck, project coordinator (Inge.Dierynck@uantwerpen.be) or Prof. Surbhi Malhotra-Kumar (Surbhi.malhotra@uantwerpen.be) .

Medical Microbiology Doctoral Scholarship Position @ Antwerp University Belgium

View Original Notification: https://www.uantwerpen.be/en/jobs/vacancies/ap/2017bapfggwef182/

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