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Molecular Genetics Scientist Position Available @ DKFZ Germany

Molecular Genetics Scientist Position Available @ DKFZ Germany

Molecular Genetics Scientist Position Available @  DKFZ Germany: The German Cancer Research Center (known as the Deutsches Krebsforschungszentrum or simply DKFZ in German), is a national cancer research center based in Heidelberg, Germany. It is a member of the Helmholtz Association of German Research Centres, the largest scientific organization in Germany.

Molecular Genetics Scientist Position Available @  DKFZ Germany

Department: Molecular Genetics

Designation: Scientist

code: 270/2016

Your tasks:

A position for a postdoctoral scientist is available in the Division of Molecular Genetics at the German Cancer Research Center (DKFZ). Our Division applies molecular profiling of cancer cell populations on the level of the genome, methylome, transcriptome, chromatin and proteome to identify the entire spectrum of alterations that may occur in a given tumor entity and to assess their clinical relevance. Integration of such data sets with clinical data allows us to identify candidate genes, which we subsequently test for their i) possible role in tumor pathophysiology, ii) potential as targets for novel therapy-strategies, iii) prognostic value to stratify patient subgroups for risk-adapted therapy regimens and iv) potential to predict therapy response or resistance in cancer patients. Within the last 5 years, we have greatly contributed to novel tumor sub-classification schemes that allow for stratification of cancer patients for different therapy regimens on the basis of molecular tumor profiles. Through the identification and functional characterization of pathogenically relevant genes, we have identified candidate targets for the development of novel therapies. We also developed pre-clinical models for the testing of novel therapies.

The successful candidate will work on an interdisciplinary project dealing with the development of animal models using cutting-edge somatic gene transfer and genome engineering approaches (e.g. CRISPR/Cas; Zuckermann et al. Nat Commun 2015; RCAS/t-va, Gronych et al. J Clin Invest. 2011). As part of the project, the candidate will also perform retrospective birth-dating of tumor cells, a method providing unique possibilities to address the question of cell turnover and assess the age of human cell populations (Ernst et al. Cell 2014). The project will answer the question of the time of origin of specific populations of tumor cells and provide fundamental insights into the biological behavior of tumors developing at different stages in life.

Your profile:

  • Applicants should hold a Ph.D. degree in biology or a related field, with a track record of relevant publications in peer-reviewed journals.
  • Candidates with strong expertise in molecular biology and genetics and experience in the planning and execution of animal experiments will be preferred.
  • The candidate should also have a strong interest in tumor biology and should be able to work in interdisciplinary teams with both internal and external partners.
  • An excellent written and oral command of English and the ability for strong teamwork is essential.
  • Names and contact information of at least two references should be provided.

Further information is available on our webpage (http://www.dkfz.de/en/genetics/index.php)

We offer:

  • Interesting, varied position
  • International environment
  • Compensation to TV-L
  • Opportunities for part-time work
  • Flexible working hours
  • Good education and training

Starts: as soon as possible


The position is limited to 2 years with the possibility of extension. The position can in principle be part-time.

Application deadline: November 16, 2016

Further information:

Dr. Aurélie Ernst / Prof. Dr. Peter Lichter
phone +49 6221 42-1512

To apply online
Apply online

The German Cancer Research Center is committed to increase the percentage of female scientists and encourages female applicants to apply. Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.

To apply for a position please use our online application portal (www.dkfz.de/jobs).

We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebsforschungszentrum, Personal- und Sozialwesen, Im Neuenheimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apologize for any inconvenience this may cause.


Molecular Genetics Scientist Position Available @  DKFZ Germany

View Original Notification: https://www.dkfz.de/en/stellenangebote/index.php?id=270/2016

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