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PhD Molecular Plant Biology @ KU Leuven | Belgium

PhD Molecular Plant Biology @ KU Leuven | Belgium

PhD Molecular Plant Biology @ KU Leuven | Belgium: Situated in Belgium, in the heart of Western Europe, KU Leuven has been a centre of learning for nearly six centuries. Today, it is Belgium’s largest university and, founded in 1425, one of the oldest and most renowned universities in Europe. As a leading European research university and co-founder of the League of European Research Universities (LERU), KU Leuven offers a wide variety of international master’s programmes, all supported by high-quality, innovative, interdisciplinary research.

PhD Molecular Plant Biology @ KU Leuven | Belgium

Since its founding, KU Leuven has been based in the city that shares its name. Leuven is a pleasant, safe and bustling student town, where centuries-rich history meets cutting-edge science. The university also offers degree programmes at campuses in 11 Belgian cities, including Brussels, Ghent and Antwerp.
SB (FWO) application in Plant proteins that assist in viral replication

(Ref. BAP-2016-416)

Occupation: Full-time

Period: Fixed-term contract

Place: Leuven

Apply no later than: August 15, 2016
We are looking for a smart and communicative student motivated to pursue a PhD in Molecular Plant Biology.
SB (FWO) application in Plant proteins that assist in viral replication

Laboratory of Molecular plant Biology

Website unit

Project

The project aims to establish a proof of concept for a novel strategy to identify plant proteins that physically interact with viral genomes and are required for viral replication and spread. This strategy uses a newly established UV cross-linking protocol to specifically induce covalent bonds between viral (RNA) genomes and host plant proteins in vivo. Subsequent highly specific probe-based isolation of viral RNA – protein complexes will allow the identification of the cross-linked plant peptides using mass spectrometry. After validation of the viral RNA – plant protein interaction in living plant cells and the subsequent assessment of a role of the plant protein in assisting viral replication, the interaction will be disrupted through targeted mutations in the corresponding plant genes. The proposed procedure could be expected to identify dominant plant genes with a function in virus susceptibility. Corresponding recessive alleles may provide allelic sources of resistance that do not affect the biochemical function in the plant. Modified plants will be phenotyped for increased virus tolerance/resistance and general performance.

Profile

We will fund the student for three months to apply for a competitive SB (FWO) scholarship. This requires a thoroughly prepared proposal, great communicative skills and strong motivation. A formal requirement is that you graduated with distinction in a masters program relevant for the application and that you have a EU passport.
http://www.fwo.be/en/fellowships-funding/phd-fellowships/doctoral-(phd)-grant-strategic-basic-research-(sb)/

Offer

Three month scholarship to apply for SB (FWO).

Interested?

For more information please contact Prof. dr. Koen Geuten, tel.: +32 16 32 15 41, mail: koen.geuten@kuleuven.be.

You can apply for this job no later than August 15, 2016 via the online application tool : http://www.kuleuven.be/eapplyingforjobs/light/53799857

PhD Molecular Plant Biology @ KU Leuven | Belgium

 

View Original Notification: https://icts.kuleuven.be/apps/jobsite/vacatures/53799857

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